Bioequivalence And Bioavailability

Topical Drug Bioavailability, Bioequivalence, and Penetration

Topical Drug Bioavailability, Bioequivalence, and Penetration by Vinod P. Shah and Howard I. Maibach
English | 2015 | ISBN: 1493912887 | 402 pages | PDF | 9 MB
Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (Repost)

Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability
Wiley-VCH | ISBN: 3527601473 |Year 2003 | English | 579pages| PDF |size: 8,99Mb

The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten.
In 21 chapters readers can benefit from the key working knowledge of today's leading pharmaceutical companies, including Pfizer, AstraZeneca, and Roche. Drug developers from industry and academia present all the factors governing drug bioavailability, complete with practical examples and real-life data.
Part I focuses on in vitro and in vivo measurements of physicochemical properties, such as membrane permeability and ionization. Part II discusses solubility and gastrointestinal absorption, while the third part is devoted to metabolism and excretory mechanisms. The much revised and expanded part IV surveys current in silico approaches to predict drug properties needed to estimate the bioavailability of any new drug candidate. The final part shows how poor bioavailability may be improved by various approaches during the development process.
No other publication offers the same level of treatment on this crucial topic in modern drug development.
Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability, Volume 40, 2nd edition (repost)

Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability, Volume 40, 2nd edition by Han van de Waterbeemd and Bernard Testa
English | 2008-11-24 | ISBN: 3527320512 | PDF | 649 pages | 4,8 MB
Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability [Repost]

Han Waterbee, Hans LenneƤs, Per Artursson - Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability
Published: 2003-08-08 | ISBN: 352730438X | PDF | 602 pages | 8.97 MB
Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (2nd edition) [Repost]

Han van de Waterbee, Beard Testa - Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (2nd edition)
Published: 2008-11-24 | ISBN: 3527320512 | PDF | 649 pages | 15.68 MB
Bioequivalence and Statistics in Clinical Pharmacology (Chapman & Hall/CRC Biostatistics Series) by Byron Jones

Bioequivalence and Statistics in Clinical Pharmacology (Chapman & Hall/CRC Biostatistics Series) by Byron Jones
English | Nov 10, 2005 | ISBN: 1584885300 | 384 Pages | PDF | 4 MB

Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology explores statistics used in day-to-day clinical pharmacology work. The book covers the methods needed to design, analyze, and interpret bioequivalence trials; explores when, how…
Dynamics and Bioavailability of Heavy Metals in the Rootzone (repost)

Dynamics and Bioavailability of Heavy Metals in the Rootzone by H. Magdi Selim
English | 2011 | ISBN: 1439826226 | 313 pages | PDF | 6 MB

Concerns regarding heavy metal contamination in terrestrial ecosystems have prompted increasing efforts on limiting their bioavailability in the root zone. The complexity of the hydrologic system gives rise to the need for understanding the fate and transport of trace elements in the soil-water-plant environment.
Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (Repost)

Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability
Wiley-VCH | 2008 | ISBN: 3527320512 | 649 pages | PDF | 5 MB

The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten.
Han van de Waterbeemd, Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability

Han van de Waterbeemd, Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability
ISBN: 352730438X | edition 2003 | PDF | 597 pages | 9 mb

The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the organism's ability to absorb pharmaceuticals by way of specific transport proteins or to excrete them. Since many pharmacologically active substances are poorly suited for oral intake, a decisive criterion for the efficacy of a medicine is its so-called bioavailability.
Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (repost)

Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability
Wiley-VCH | 2008 | ISBN: 3527320512 | 649 pages | PDF | 4,4 MB